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  1. The eastcoast of the USA where artists like Jay-Z, Cam'ron, Nas, Biggie, Fat Joe, and Rakim are from.
  2. The eastside of any city, like the eastside of LA that Cypress Hill mentions: Eastside!, that's right nigga!, east motherfucking side. -- Cypress Hill (Killa).
  3. eastside got cities like baltimore, detroit, newyork and dc and PHILLY

Also see

50 cent and G unit reppin eastside holla Lil' Youngin reppin DC soufeast