From Rap Dictionary
- To play a hip-hop record at a slower speed, said to accentuate the bass and facilitate mixes with ballads and to accompany the fad of sippin syrup. Also screw mixes, get my screw on. Originated in the late 80's, when Fresh Records released 12" singles at 45 rpm. Many DJ's missed the speed designation and mistakenly played it at the slower 33 rpm speed. Many listeners began to intentionally request those records (esp. Mantronix's "Fresh is the Word") at the slow speed. They term screwed may also have originated from a custom screw on a tape deck allowing adjustment of the pitch. Now done with CD players with variable pitch (or vinyl). Made popular by DJ Screw. See also: Michael Watts, Swisha House.
- To have sexual intercourse.
- "Screw someone over" means to betray or disappoint someone.